It is well known that miRNAs are involved in many essential cellular processes, such as cell proliferation, differentiation, apoptosis, stress response and tumorigenesis etc. MiRNAs function in RNA silencing and post-transcriptional regulation of gene expression. Mature miRNAs assemble into RNA-induced silencing complex (RISC), guide the complex to target messenger RNAs (mRNAs), and regulate their expression either by cleavage of target mRNA or by translation inhibition.

#54219 5. decembra 2023 o 9:33